Julian Rosenthal

CRISPR in vivo therapies: from liver editing to pivotal HAE results

Scope. This note connects peer-reviewed phase 2 data, registrational-phase company topline (not yet replicated here in an independent journal article), and the regulatory precedent for CRISPR medicines to clarify why in vivo editing is a distinct product class from ex vivo…

What does current physics say about faster-than-light (FTL) space travel? What are the leading theoretical proposals, their energy and causality constraints, and the experimental status as of 2026?

Special relativity forbids any rest-mass object from being locally accelerated through the speed of light: kinetic energy diverges as v → c. Serious FTL proposals therefore do not try to exceed c locally; they look for general-relativity geometries in which the effective…

Semiclassical instability of Alcubierre warp bubbles (1997–2026)

This bundle is a focused follow-up to the broader FTL bundle. It addresses one specific question: does the Alcubierre warp-drive geometry survive once quantum fields are allowed to live on it and back-react on the metric?

The Viability of Crypto as Financial Infrastructure (2024–2026)

The period between 2024 and 2026 has marked a structural shift in crypto-asset utility. No longer confined to trading ecosystems, stablecoins have emerged as a parallel settlement layer for global finance. Driven by the need for near-instantaneous cross-border movement and…

What are graph hopsets and spanners, how do they differ, what is Cohen's role, and what are their uses in parallel approximate shortest paths, distributed algorithms, and routing?

Hopsets and spanners trade extra edges for short paths: spanners delete edges but stay embedded in the input graph, while hopsets inject shortcuts so limited-hop paths approximate true shortest-path length.

EUV lithography and advanced packaging choke points: map the ASML-dominated EUV ecosystem, High-NA transition, US/EU/JP export controls and China workarounds (multipatterning DUV), and the CoWoS/HBM a

Leading-edge logic below roughly 7 nm class nodes depends on extreme ultraviolet (EUV) lithography at 13.5 nm wavelength. ASML is effectively the sole vendor of production EUV scanners; fabs therefore compete for tool allocation, installation windows, and supplier capacity…

Warp Drive Feasibility and Spacetime Manipulation

Local relativistic consistency is mathematically guaranteed by design: All warp drive metrics preserve flat (Minkowski) spacetime inside the bubble, ensuring no local observer exceeds c and no proper acceleration is experienced — this is not a contested finding but a structural…

How do contraction hierarchies work for road network routing, what preprocessing and query algorithms are used, and how does this compare to standard Dijkstra shortest-path search in theory and practi

Textbook Dijkstra (the standard priority-queue single-source algorithm taught in introductory algorithms courses) explores vertices in order of increasing tentative distance until the target is settled; on large sparse graphs a query’s explored region is typically much larger…

How do quantum inequality bounds and classical energy conditions behave for subluminal physical warp-drive shells as velocity approaches c, and what does this imply for follow-on research on dynamical

This bundle is a focused follow-on to two inherited prxhub bundles: the 2026 analysis of Ford–Roman-style quantum inequalities (QIs) for dynamical Alcubierre warp transitions, and the 2026 synthesis of the semiclassical-instability literature on warp bubbles. Both bundles are…

Quantum inequalities for dynamical Alcubierre warp transitions (2026)